Genomics Training for Biomedical Scientists UK: GTAC, Courses, and Career Opportunities
Genomics Training for Biomedical Scientists UK: GTAC, Courses, and Career Opportunities
Genomics has become one of the fastest-growing areas of laboratory medicine in the UK, driven by the NHS Genomic Medicine Service and the legacy of the 100,000 Genomes Project. For biomedical scientists looking to move into this field, there are clear training pathways, dedicated courses, and expanding career opportunities. Understanding how to access genomics training and where it can take your career is increasingly important.
Genomics England and the NHS Genomic Medicine Service
The UK is a global leader in clinical genomics. Genomics England, established in 2013, delivered the 100,000 Genomes Project and continues to drive the integration of genomic data into patient care. Building on this, NHS England launched the NHS Genomic Medicine Service (GMS) to embed genomics into routine clinical practice.
The GMS operates through a network of seven Genomic Laboratory Hubs (GLHs) across England, each serving a defined population. These hubs are the primary employers of biomedical scientists working in genomics and include:
- North Thames GLH (Great Ormond Street Hospital)
- South Thames GLH (Guy's and St Thomas')
- East GLH (Cambridge University Hospitals)
- North West GLH (Manchester University NHS Foundation Trust)
- Central and South GLH (Birmingham Women's and Children's)
- South West GLH (North Bristol NHS Trust)
- North East and Yorkshire GLH (Leeds Teaching Hospitals)
The Genomics Training Academy (GTAC)
The Genomics Training Academy (GTAC), funded by Health Education England (now NHS England Workforce, Training and Education), provides specialist genomics education for the NHS workforce.
What GTAC Offers
- Short courses covering topics such as next-generation sequencing (NGS), variant interpretation, bioinformatics, and clinical genomics applications
- Blended learning combining online modules with face-to-face practical sessions
- Specialty-specific training in areas including cancer genomics, rare disease, pharmacogenomics, and reproductive genomics
- Resources for non-genetics professionals to build foundational genomics knowledge
MSc Genomic Medicine Programmes
For a more comprehensive qualification, several UK universities offer MSc Genomic Medicine programmes. These are typically part-time to accommodate working professionals and cover:
- Molecular genetics and genomic technologies
- Bioinformatics and data analysis
- Variant classification and interpretation
- Clinical applications across specialties
- Ethical, legal, and social implications of genomics
The HEE Genomics Education Programme (GEP) has also developed a range of educational resources and supports the Scientist Training Programme (STP) in genomics.
How Biomedical Scientists Can Move into Genomics
Crossover Specialties
Several biomedical science specialties provide natural pathways into genomics:
- Haematology: Molecular haematology already involves techniques such as PCR for BCR-ABL monitoring, JAK2 mutation testing, and increasingly NGS panels for myeloid malignancies
- Molecular pathology: Direct overlap with genomic technologies and techniques
- Microbiology: Whole genome sequencing (WGS) for outbreak investigation and antimicrobial resistance profiling
- Histopathology: Molecular testing on tissue samples for targeted cancer therapies
Building Your Skill Set
To transition into genomics, focus on developing:
- Molecular biology techniques: PCR, Sanger sequencing, NGS library preparation
- Bioinformatics basics: Understanding of sequence alignment, variant calling, and database searching (ClinVar, gnomAD, COSMIC)
- Variant interpretation: Classifying variants according to ACMG/ACGS guidelines
- Quality management: ISO 15189 compliance for molecular and genomic testing
Salary and Career Progression
Genomics roles for biomedical scientists are typically graded at:
- Band 5 (£29,970-£36,483): Newly qualified BMS in a genomics laboratory, performing routine molecular testing
- Band 6 (£37,338-£44,962): Specialist BMS with experience in NGS, variant analysis, or specific disease areas
- Band 7 (£46,148-£52,809): Section lead or specialist scientist with advanced expertise, often responsible for service development and validation of new tests
- Band 8a (£53,755-£60,504): Principal scientist or laboratory manager roles within GLHs
Career Opportunities
The genomics workforce is expanding. Current and emerging roles include:
- Genomic Scientist: Performing and interpreting genomic tests within a GLH
- Bioinformatics Scientist: Developing and managing analysis pipelines (requires additional computational training)
- Variant Scientist: Specialising in variant interpretation and classification
- Genomic Counsellor/Associate: Supporting patients and families (requires specific genetic counselling training)
- Research Scientist: Working at the interface of clinical service and research within organisations such as Genomics England
Key Points
- The NHS Genomic Medicine Service operates through seven GLHs across England, all employing biomedical scientists
- GTAC provides free or subsidised short courses in genomics topics, ideal for initial exploration
- MSc Genomic Medicine programmes are available part-time at several UK universities
- Haematology, molecular pathology, and microbiology provide natural crossover routes into genomics
- Key skills to develop include NGS techniques, bioinformatics basics, and variant interpretation
- Roles are available from Band 5 to Band 8a within GLHs, with an expanding workforce
- The HEE Genomics Education Programme and Scientist Training Programme offer additional training and career routes